Chronic Dietary Toxicity/Oncogenicity Studies on 2,4-Dichlorophenoxyacetic Acid in Rodents

Chronic dietary toxicity/oncogenicity studies on 2,4-dichlorophenoxybutyric acid in rodents.

2,4-Dichlorophenoxybutyric acid (2,4-DB) is principally used in the United States on peanuts, soybeans, and alfalfa. In Europe, it is used on cereals, undersown cereals, lucerne (alfalfa), clover, and clover mixtures. Doses in the 2-year chronic/oncogenicity rat study were 0, 60, 600, and 1800 ppm. No evidence of an oncogenic potential for 2,4-DB was evident and the study clearly established a ...

The Effect of Dietary Polyunsaturated Fatty Acid on Skin Wound Healing in Chronic Diabetic Rat

The potential role of omega – 3 (ω-3) and omega - 6(ω-6) fatty acids on wound healing is of interest and controversial. In the present study, the effect of dietary intake of fish oil (ω-3 diet ) and corn oil (ω-6 diet) on skin wound healing has been investigated in rat. This experimental study was performed on four groups of male rats (one normal group and three diabetic groups). Diabetes was i...

Industrial toxicology; 2,4-dichlorophenoxyacetic acid.

Metabolism of 2,4-dichlorophenoxyacetic Acid in 2,4-dichlorophenoxyacetic Acid-resistant soybean callus tissue.

Three 2,4-dichlorophenoxyacetic acid (2,4-D) -resistant root callus tissue lines of Glycine max L. Merrill var. Acme were derived by culturing callus tissue 2 to 6 months on 40 milligrams per liter 2,4-D and designated 40R, 40B, and 40C. Tissue line 40R had a lower level of 2,4-D uptake in 2-week-old tissue which disappeared in 3.5-week-old tissue and less free 2,4-D following incubation for 24...

Effect of 2,4-dichlorophenoxyacetic Acid on Meristematic Tissues of Corn.

In recent years the use of 2,4-dichlorophenoxyacetic acid (2,4-D) as a selective herbicide has become increasingly important in the production of small grains and corn. Yield reductions due to direct injury to the crops are usually small. However, severe yield reductions have occurred occasionally when 2,4-D was used at herbicidal dosages during certain stages of crop growth. Corn plants spraye...